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Closing and opening of the RNA polymerase trigger loop

The RNA polymerase (RNAP) trigger loop (TL) is a mobile structural element of the RNAP active center that, based on crystal structures, has been proposed to cycle between an “unfolded”/“open” state that allows an NTP substrate to enter the active center and a “folded”/“closed” state that holds the N...

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Detalles Bibliográficos
Autores principales: Mazumder, Abhishek, Lin, Miaoxin, Kapanidis, Achillefs N., Ebright, Richard H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355006/
https://www.ncbi.nlm.nih.gov/pubmed/32571927
http://dx.doi.org/10.1073/pnas.1920427117