Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation

Burkholderia pseudomallei is the causative agent of melioidosis, an infectious disease in the tropics and subtropics with high morbidity and mortality. The facultative intracellular bacterium induces host cell fusion through its type VI secretion system 5 (T6SS5) as an important part of its pathogen...

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Detalles Bibliográficos
Autores principales: Ku, Joanne Wei Kay, Chen, Yahua, Lim, Bryan Jian Wei, Gasser, Stephan, Crasta, Karen Carmelina, Gan, Yunn-Hwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355030/
https://www.ncbi.nlm.nih.gov/pubmed/32571920
http://dx.doi.org/10.1073/pnas.2006908117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355030/
https://www.ncbi.nlm.nih.gov/pubmed/32571920
http://dx.doi.org/10.1073/pnas.2006908117

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