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Bacterial-induced cell fusion is a danger signal triggering cGAS–STING pathway via micronuclei formation
Burkholderia pseudomallei is the causative agent of melioidosis, an infectious disease in the tropics and subtropics with high morbidity and mortality. The facultative intracellular bacterium induces host cell fusion through its type VI secretion system 5 (T6SS5) as an important part of its pathogen...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355030/ https://www.ncbi.nlm.nih.gov/pubmed/32571920 http://dx.doi.org/10.1073/pnas.2006908117 |