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Up-regulated cytotrophoblast DOCK4 contributes to over-invasion in placenta accreta spectrum

In humans, a subset of placental cytotrophoblasts (CTBs) invades the uterus and its vasculature, anchoring the pregnancy and ensuring adequate blood flow to the fetus. Appropriate depth is critical. Shallow invasion increases the risk of pregnancy complications, e.g., severe preeclampsia. Overly dee...

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Detalles Bibliográficos
Autores principales: McNally, Leah, Zhou, Yan, Robinson, Joshua F., Zhao, Guangfeng, Chen, Lee-may, Chen, Hao, Kim, M. Yvonne, Kapidzic, Mirhan, Gormley, Matthew, Hannibal, Roberta, Fisher, Susan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355036/
https://www.ncbi.nlm.nih.gov/pubmed/32576693
http://dx.doi.org/10.1073/pnas.1920776117