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A Novel Chemically Differentiated Mouse Embryonic Stem Cell-Based Model to Study Liver Stages of Plasmodium berghei

Asymptomatic and obligatory liver stage (LS) infection of Plasmodium parasites presents an attractive target for antimalarial vaccine and drug development. Lack of robust cellular models to study LS infection has hindered the discovery and validation of host genes essential for intrahepatic parasite...

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Detalles Bibliográficos
Autores principales: Tripathi, Jaishree, Segeritz, Charis-Patricia, Griffiths, Gareth, Bushell, Wendy, Vallier, Ludovic, Skarnes, William C., Mota, Maria M., Billker, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355138/
https://www.ncbi.nlm.nih.gov/pubmed/32442532
http://dx.doi.org/10.1016/j.stemcr.2020.04.010