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A Novel Chemically Differentiated Mouse Embryonic Stem Cell-Based Model to Study Liver Stages of Plasmodium berghei
Asymptomatic and obligatory liver stage (LS) infection of Plasmodium parasites presents an attractive target for antimalarial vaccine and drug development. Lack of robust cellular models to study LS infection has hindered the discovery and validation of host genes essential for intrahepatic parasite...
Autores principales: | Tripathi, Jaishree, Segeritz, Charis-Patricia, Griffiths, Gareth, Bushell, Wendy, Vallier, Ludovic, Skarnes, William C., Mota, Maria M., Billker, Oliver |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355138/ https://www.ncbi.nlm.nih.gov/pubmed/32442532 http://dx.doi.org/10.1016/j.stemcr.2020.04.010 |
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