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A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture

Multiple protocols have been published for generation of iMGLs from hESCs/iPSCs. To date, there are no guides to assist researchers to determine the most appropriate methodology for microglial studies. To establish a framework to facilitate future microglial studies, we first performed a comparative...

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Detalles Bibliográficos
Autores principales: Grubman, Alexandra, Vandekolk, Teresa H., Schröder, Jan, Sun, Guizhi, Hatwell-Humble, Jessica, Chan, Jonathan, Oksanen, Minna, Lehtonen, Sarka, Hunt, Cameron, Koistinaho, Jari E., Nilsson, Susan K., Haynes, John M., Pouton, Colin W., Polo, Jose M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355140/
https://www.ncbi.nlm.nih.gov/pubmed/32442534
http://dx.doi.org/10.1016/j.stemcr.2020.04.007