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A CX3CR1 Reporter hESC Line Facilitates Integrative Analysis of In-Vitro-Derived Microglia and Improved Microglia Identity upon Neuron-Glia Co-culture
Multiple protocols have been published for generation of iMGLs from hESCs/iPSCs. To date, there are no guides to assist researchers to determine the most appropriate methodology for microglial studies. To establish a framework to facilitate future microglial studies, we first performed a comparative...
Autores principales: | Grubman, Alexandra, Vandekolk, Teresa H., Schröder, Jan, Sun, Guizhi, Hatwell-Humble, Jessica, Chan, Jonathan, Oksanen, Minna, Lehtonen, Sarka, Hunt, Cameron, Koistinaho, Jari E., Nilsson, Susan K., Haynes, John M., Pouton, Colin W., Polo, Jose M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355140/ https://www.ncbi.nlm.nih.gov/pubmed/32442534 http://dx.doi.org/10.1016/j.stemcr.2020.04.007 |
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