Human Cerebrospinal Fluid Promotes Neuronal Circuit Maturation of Human Induced Pluripotent Stem Cell-Derived 3D Neural Aggregates

Human induced pluripotent stem cell (hiPSC)-derived in vitro neural and organoid models resemble fetal, rather than adult brain properties, indicating that currently applied cultivation media and supplements are insufficient to achieve neural maturation beyond the fetal stage. In vivo, cerebrospinal...

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Detalles Bibliográficos
Autores principales: Izsak, Julia, Seth, Henrik, Theiss, Stephan, Hanse, Eric, Illes, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355159/
https://www.ncbi.nlm.nih.gov/pubmed/32521247
http://dx.doi.org/10.1016/j.stemcr.2020.05.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355159/
https://www.ncbi.nlm.nih.gov/pubmed/32521247
http://dx.doi.org/10.1016/j.stemcr.2020.05.006

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