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ClonArch: visualizing the spatial clonal architecture of tumors
MOTIVATION: Cancer is caused by the accumulation of somatic mutations that lead to the formation of distinct populations of cells, called clones. The resulting clonal architecture is the main cause of relapse and resistance to treatment. With decreasing costs in DNA sequencing technology, rich cance...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355227/ https://www.ncbi.nlm.nih.gov/pubmed/32657368 http://dx.doi.org/10.1093/bioinformatics/btaa471 |