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Mutational signature learning with supervised negative binomial non-negative matrix factorization
MOTIVATION: Understanding the underlying mutational processes of cancer patients has been a long-standing goal in the community and promises to provide new insights that could improve cancer diagnoses and treatments. Mutational signatures are summaries of the mutational processes, and improving the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355241/ https://www.ncbi.nlm.nih.gov/pubmed/32657388 http://dx.doi.org/10.1093/bioinformatics/btaa473 |