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Identifying tumor clones in sparse single-cell mutation data
MOTIVATION: Recent single-cell DNA sequencing technologies enable whole-genome sequencing of hundreds to thousands of individual cells. However, these technologies have ultra-low sequencing coverage (<0.5× per cell) which has limited their use to the analysis of large copy-number aberrations (CNA...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355247/ https://www.ncbi.nlm.nih.gov/pubmed/32657385 http://dx.doi.org/10.1093/bioinformatics/btaa449 |