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Unsupervised topological alignment for single-cell multi-omics integration

MOTIVATION: Single-cell multi-omics data provide a comprehensive molecular view of cells. However, single-cell multi-omics datasets consist of unpaired cells measured with distinct unmatched features across modalities, making data integration challenging. RESULTS: In this study, we present a novel a...

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Detalles Bibliográficos
Autores principales: Cao, Kai, Bai, Xiangqi, Hong, Yiguang, Wan, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355262/
https://www.ncbi.nlm.nih.gov/pubmed/32657382
http://dx.doi.org/10.1093/bioinformatics/btaa443