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Hopper: a mathematically optimal algorithm for sketching biological data

MOTIVATION: Single-cell RNA-sequencing has grown massively in scale since its inception, presenting substantial analytic and computational challenges. Even simple downstream analyses, such as dimensionality reduction and clustering, require days of runtime and hundreds of gigabytes of memory for tod...

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Detalles Bibliográficos
Autores principales: DeMeo, Benjamin, Berger, Bonnie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355272/
https://www.ncbi.nlm.nih.gov/pubmed/32657375
http://dx.doi.org/10.1093/bioinformatics/btaa408