Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates

Buprenorphine plays a crucial role in the therapeutic management of pain in adults, adolescents and pediatric subpopulations. However, only few pharmacokinetic studies of buprenorphine in children, particularly neonates, are available as conducting clinical trials in this population is especially ch...

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Detalles Bibliográficos
Autores principales: Kovar, Lukas, Schräpel, Christina, Selzer, Dominik, Kohl, Yvonne, Bals, Robert, Schwab, Matthias, Lehr, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355427/
https://www.ncbi.nlm.nih.gov/pubmed/32585880
http://dx.doi.org/10.3390/pharmaceutics12060578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355427/
https://www.ncbi.nlm.nih.gov/pubmed/32585880
http://dx.doi.org/10.3390/pharmaceutics12060578

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