Cargando…

Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation

Urease is a nickel-containing enzyme that is essential for the survival of several and often deadly pathogenic bacterial strains, including Helicobacter pylori. Notwithstanding several attempts, the development of direct urease inhibitors without side effects for the human host remains, to date, elu...

Descripción completa

Detalles Bibliográficos
Autores principales: Masetti, Matteo, Falchi, Federico, Gioia, Dario, Recanatini, Maurizio, Ciurli, Stefano, Musiani, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355429/
https://www.ncbi.nlm.nih.gov/pubmed/32599898
http://dx.doi.org/10.3390/molecules25122911