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Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation
Urease is a nickel-containing enzyme that is essential for the survival of several and often deadly pathogenic bacterial strains, including Helicobacter pylori. Notwithstanding several attempts, the development of direct urease inhibitors without side effects for the human host remains, to date, elu...
Autores principales: | Masetti, Matteo, Falchi, Federico, Gioia, Dario, Recanatini, Maurizio, Ciurli, Stefano, Musiani, Francesco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355429/ https://www.ncbi.nlm.nih.gov/pubmed/32599898 http://dx.doi.org/10.3390/molecules25122911 |
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