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Saturation Mutagenesis for Phenylalanine Ammonia Lyases of Enhanced Catalytic Properties
Phenylalanine ammonia-lyases (PALs) are attractive biocatalysts for the stereoselective synthesis of non-natural phenylalanines. The rational design of PALs with extended substrate scope, highlighted the substrate specificity-modulator role of residue I460 of Petroselinum crispum PAL. Herein, satura...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355458/ https://www.ncbi.nlm.nih.gov/pubmed/32486192 http://dx.doi.org/10.3390/biom10060838 |