Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax

Increasing numbers of beyond Rule-of-Five drugs are emerging from discovery pipelines, generating a need for bio-enabling formulation approaches, such as lipid-based formulations (LBF), to ensure maximal in vivo exposure. However, many drug candidates display insufficient lipid solubility, leading t...

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Detalles Bibliográficos
Autores principales: Koehl, Niklas J., Henze, Laura J., Kuentz, Martin, Holm, René, Griffin, Brendan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355533/
https://www.ncbi.nlm.nih.gov/pubmed/32570753
http://dx.doi.org/10.3390/pharmaceutics12060564

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355533/
https://www.ncbi.nlm.nih.gov/pubmed/32570753
http://dx.doi.org/10.3390/pharmaceutics12060564

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