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Preparation of a First (18)F-Labeled Agonist for M(1) Muscarinic Acetylcholine Receptors

M(1) muscarinic acetylcholine receptors (mAChRs) are abundant in postsynaptic nerve terminals of all forebrain regions and have been implicated in the cognitive decline associated with Alzheimer’s disease and other CNS pathologies. Consequently, major efforts have been spent in the development of su...

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Detalles Bibliográficos
Autores principales: Zlatopolskiy, Boris D., Neumaier, Felix, Rüngeler, Till, Drewes, Birte, Kolks, Niklas, Neumaier, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355535/
https://www.ncbi.nlm.nih.gov/pubmed/32585815
http://dx.doi.org/10.3390/molecules25122880