Design and Characterization of Spray-Dried Chitosan-Naltrexone Microspheres for Microneedle-Assisted Transdermal Delivery

Naltrexone (NTX) hydrochloride is a potent opioid antagonist with significant first-pass metabolism and notable untoward effects when administered orally or intramuscularly. Microneedle (MN)-assisted transdermal delivery is an attractive alternative that can improve therapeutic delivery to deeper sk...

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Detalles Bibliográficos
Autores principales: Ogunjimi, Abayomi T., Fiegel, Jennifer, Brogden, Nicole K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355536/
https://www.ncbi.nlm.nih.gov/pubmed/32485999
http://dx.doi.org/10.3390/pharmaceutics12060496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355536/
https://www.ncbi.nlm.nih.gov/pubmed/32485999
http://dx.doi.org/10.3390/pharmaceutics12060496

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