Influence of the Polymer Glass Transition Temperature and Molecular Weight on Drug Amorphization Kinetics Using Ball Milling

In this study, the putative correlation between the molecular mobility of a polymer and the ball milling drug amorphization kinetics (i.e., time to reach full drug amorphization, t(a)) was studied using different grades of dextran (Dex) and polyvinylpyrrolidone (PVP) and the two model drugs indometh...

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Detalles Bibliográficos
Autores principales: Asgreen, Camilla, Knopp, Matthias Manne, Skytte, Jeppe, Löbmann, Korbinian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355600/
https://www.ncbi.nlm.nih.gov/pubmed/32471023
http://dx.doi.org/10.3390/pharmaceutics12060483

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355600/
https://www.ncbi.nlm.nih.gov/pubmed/32471023
http://dx.doi.org/10.3390/pharmaceutics12060483

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