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Redox-Dependent Copper Ion Modulation of Amyloid-β (1-42) Aggregation In Vitro

Plaque deposits composed of amyloid-β (Aβ) fibrils are pathological hallmarks of Alzheimer’s disease (AD). Although copper ion dyshomeostasis is apparent in AD brains and copper ions are found co-deposited with Aβ peptides in patients’ plaques, the molecular effects of copper ion interactions and re...

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Detalles Bibliográficos
Autores principales: Sasanian, Nima, Bernson, David, Horvath, Istvan, Wittung-Stafshede, Pernilla, Esbjörner, Elin K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355640/
https://www.ncbi.nlm.nih.gov/pubmed/32570820
http://dx.doi.org/10.3390/biom10060924