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Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ

How sequences of intrinsically disordered proteins (IDPs) code for their conformational dynamics is poorly understood. Here, we combined NMR spectroscopy, small-angle X-ray scattering (SAXS), and molecular dynamics (MD) simulations to characterize the conformations and dynamics of ChiZ1-64. MD simul...

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Detalles Bibliográficos
Autores principales: Hicks, Alan, Escobar, Cristian A., Cross, Timothy A., Zhou, Huan-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355643/
https://www.ncbi.nlm.nih.gov/pubmed/32585849
http://dx.doi.org/10.3390/biom10060946