Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2

Hyperactivation of microglia in the brain is closely related to neuroinflammation and leads to neuronal dysfunction. Costunolide (CTL) is a natural sesquiterpene lactone with wide pharmacological activities including anti-inflammation and antioxidation. In this study, we found that CTL significantly...

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Detalles Bibliográficos
Autores principales: Liu, Yan-Chen, Feng, Na, Li, Wei-Wei, Tu, Peng-Fei, Chen, Jian-Ping, Han, Jing-Yan, Zeng, Ke-Wu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355650/
https://www.ncbi.nlm.nih.gov/pubmed/32575562
http://dx.doi.org/10.3390/molecules25122840

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355650/
https://www.ncbi.nlm.nih.gov/pubmed/32575562
http://dx.doi.org/10.3390/molecules25122840

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