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Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2
Hyperactivation of microglia in the brain is closely related to neuroinflammation and leads to neuronal dysfunction. Costunolide (CTL) is a natural sesquiterpene lactone with wide pharmacological activities including anti-inflammation and antioxidation. In this study, we found that CTL significantly...
Autores principales: | Liu, Yan-Chen, Feng, Na, Li, Wei-Wei, Tu, Peng-Fei, Chen, Jian-Ping, Han, Jing-Yan, Zeng, Ke-Wu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355650/ https://www.ncbi.nlm.nih.gov/pubmed/32575562 http://dx.doi.org/10.3390/molecules25122840 |
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