Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs

Interactions between drugs and melanin pigment may have major impacts on pharmacokinetics. Therefore, melanin binding can modify the efficacy and toxicity of medications in ophthalmic and other disease of pigmented tissues, such as melanoma. As melanin is present in many pigmented tissues in the hum...

Descripción completa

Detalles Bibliográficos
Autores principales: Hellinen, Laura, Bahrpeyma, Sina, Rimpelä, Anna-Kaisa, Hagström, Marja, Reinisalo, Mika, Urtti, Arto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355663/
https://www.ncbi.nlm.nih.gov/pubmed/32560065
http://dx.doi.org/10.3390/pharmaceutics12060554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355663/
https://www.ncbi.nlm.nih.gov/pubmed/32560065
http://dx.doi.org/10.3390/pharmaceutics12060554

Ejemplares similares