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Microscale Thermophoresis as a Screening Tool to Predict Melanin Binding of Drugs
Interactions between drugs and melanin pigment may have major impacts on pharmacokinetics. Therefore, melanin binding can modify the efficacy and toxicity of medications in ophthalmic and other disease of pigmented tissues, such as melanoma. As melanin is present in many pigmented tissues in the hum...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355663/ https://www.ncbi.nlm.nih.gov/pubmed/32560065 http://dx.doi.org/10.3390/pharmaceutics12060554 |