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Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production

One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors based on solid lipid nanoparticles (SLNs) as gene delivery systems to induce the...

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Detalles Bibliográficos
Autores principales: Vicente-Pascual, Mónica, Gómez-Aguado, Itziar, Rodríguez-Castejón, Julen, Rodríguez-Gascón, Alicia, Muntoni, Elisabetta, Battaglia, Luigi, del Pozo-Rodríguez, Ana, Solinís Aspiazu, María Ángeles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355708/
https://www.ncbi.nlm.nih.gov/pubmed/32586018
http://dx.doi.org/10.3390/pharmaceutics12060584