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Topical Administration of SLN-Based Gene Therapy for the Treatment of Corneal Inflammation by De Novo IL-10 Production
One of the main challenges in gene therapy is the issue of delivery, and it is especially relevant for the success of gene therapy in the cornea. In the present work, eye drops containing biocompatible non-viral vectors based on solid lipid nanoparticles (SLNs) as gene delivery systems to induce the...
Autores principales: | Vicente-Pascual, Mónica, Gómez-Aguado, Itziar, Rodríguez-Castejón, Julen, Rodríguez-Gascón, Alicia, Muntoni, Elisabetta, Battaglia, Luigi, del Pozo-Rodríguez, Ana, Solinís Aspiazu, María Ángeles |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355708/ https://www.ncbi.nlm.nih.gov/pubmed/32586018 http://dx.doi.org/10.3390/pharmaceutics12060584 |
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