Impaired Mitochondrial Morphology and Functionality in Lonp1(wt/−) Mice

LONP1 is a nuclear-encoded mitochondrial protease crucial for organelle homeostasis; mutations of LONP1 have been associated with Cerebral, Ocular, Dental, Auricular, and Skeletal anomalies (CODAS) syndrome. To clarify the role of LONP1 in vivo, we generated a mouse model in which Lonp1 was ablated....

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Detalles Bibliográficos
Autores principales: De Gaetano, Anna, Gibellini, Lara, Bianchini, Elena, Borella, Rebecca, De Biasi, Sara, Nasi, Milena, Boraldi, Federica, Cossarizza, Andrea, Pinti, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355737/
https://www.ncbi.nlm.nih.gov/pubmed/32521756
http://dx.doi.org/10.3390/jcm9061783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355737/
https://www.ncbi.nlm.nih.gov/pubmed/32521756
http://dx.doi.org/10.3390/jcm9061783

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