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Synthesis, Cyclooxygenases Inhibition Activities and Interactions with BSA of N-substituted 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones Derivatives

Inhibition of cyclooxygenase is the way of therapeutic activities for anti-inflammatory pharmaceuticals. Serum albumins are the major soluble protein able to bind and transport a variety of exogenous and endogenous ligands, including hydrophobic pharmaceuticals. In this study, a novel N-substituted...

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Detalles Bibliográficos
Autores principales: Krzyżak, Edward, Szkatuła, Dominika, Wiatrak, Benita, Gębarowski, Tomasz, Marciniak, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355801/
https://www.ncbi.nlm.nih.gov/pubmed/32630594
http://dx.doi.org/10.3390/molecules25122934