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Asymmetric Synthesis of Photophore-Containing Lactisole Derivatives to Elucidate Sweet Taste Receptors

Lactisole, which has a 2-phenoxy propionic acid skeleton, is well-known as an inhibitor of sweet taste receptors. We recently revealed some of the structure–activity relationships of the aromatic ring and chiral center of lactisole. Photoaffinity labeling is one of the common chemical biology method...

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Detalles Bibliográficos
Autores principales: Nakagita, Tomoya, Ishida, Akiko, Tachrim, Zetryana Puteri, Wang, Lei, Misaka, Takumi, Hashimoto, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355818/
https://www.ncbi.nlm.nih.gov/pubmed/32560345
http://dx.doi.org/10.3390/molecules25122790