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Characterization of Hepatitis B Surface Antigen Loaded Polylactic Acid-Based Microneedle and Its Dermal Safety Profile

A surge of interest in microneedle (MN) vaccines as a novel vaccination system has emerged. Before the clinical application of MN vaccine, an assessment of potential biological risks to skin and quality control of MN must be performed. Therefore, the present study aims to evaluate the physicochemica...

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Detalles Bibliográficos
Autores principales: Na, Young-Guk, Kim, Minki, Han, Mingu, Huh, Hyun Wook, Kim, Ji-Seok, Kim, Jong Chan, Park, Jung-Hwan, Lee, Hong-Ki, Cho, Cheong-Weon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355901/
https://www.ncbi.nlm.nih.gov/pubmed/32527003
http://dx.doi.org/10.3390/pharmaceutics12060531