Understand the Specific Regio- and Enantioselectivity of Fluostatin Conjugation in the Post-Biosynthesis

Fluostatins, benzofluorene-containing aromatic polyketides in the atypical angucycline family, conjugate into dimeric and even trimeric compounds in the post-biosynthesis. The formation of the C–C bond involves a non-enzymatic stereospecific coupling reaction. In this work, the unusual regio- and en...

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Detalles Bibliográficos
Autores principales: Wang, Yuanqi, Zhang, Changsheng, Zhao, Yi-Lei, Zhao, Rosalinda, Houk, Kendall N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355926/
https://www.ncbi.nlm.nih.gov/pubmed/32466453
http://dx.doi.org/10.3390/biom10060815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355926/
https://www.ncbi.nlm.nih.gov/pubmed/32466453
http://dx.doi.org/10.3390/biom10060815

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