Examining the Effects of (α4)3(β2)2 Nicotinic Acetylcholine Receptor-Selective Positive Allosteric Modulator on Acute Thermal Nociception in Rats

Neuronal nicotinic acetylcholine receptor (nAChR)-based therapeutics are sought as a potential alternative strategy to opioids for pain management. In this study, we examine the antinociceptive effects of 3-(2-chlorophenyl)-5-(5-methyl-1-(piperidin-4-yl)-1H-pyrazol-4-yl)isoxazole (CMPI), a novel pos...

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Detalles Bibliográficos
Autores principales: Deba, Farah, Ramos, Kara, Vannoy, Matthew, Munoz, Kemburli, Akinola, Lois S., Damaj, M. Imad, Hamouda, Ayman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355939/
https://www.ncbi.nlm.nih.gov/pubmed/32630476
http://dx.doi.org/10.3390/molecules25122923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355939/
https://www.ncbi.nlm.nih.gov/pubmed/32630476
http://dx.doi.org/10.3390/molecules25122923

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