Metallo-β-Lactamase Inhibitors Inspired on Snapshots from the Catalytic Mechanism

β-Lactam antibiotics are the most widely prescribed antibacterial drugs due to their low toxicity and broad spectrum. Their action is counteracted by different resistance mechanisms developed by bacteria. Among them, the most common strategy is the expression of β-lactamases, enzymes that hydrolyze...

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Detalles Bibliográficos
Autores principales: Palacios, Antonela R., Rossi, María-Agustina, Mahler, Graciela S., Vila, Alejandro J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356002/
https://www.ncbi.nlm.nih.gov/pubmed/32503337
http://dx.doi.org/10.3390/biom10060854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356002/
https://www.ncbi.nlm.nih.gov/pubmed/32503337
http://dx.doi.org/10.3390/biom10060854

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