Transcription Factor Nrf2 as a Potential Therapeutic Target for Prevention of Cytokine Storm in COVID-19 Patients

Nrf2 is a key transcription factor responsible for antioxidant defense in many tissues and cells, including alveolar epithelium, endothelium, and macrophages. Furthermore, Nrf2 functions as a transcriptional repressor that inhibits expression of the inflammatory cytokines in macrophages. Critically...

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Detalles Bibliográficos
Autores principales: Zinovkin, R. A., Grebenchikov, O. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2020
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356136/
https://www.ncbi.nlm.nih.gov/pubmed/33040727
http://dx.doi.org/10.1134/S0006297920070111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356136/
https://www.ncbi.nlm.nih.gov/pubmed/33040727
http://dx.doi.org/10.1134/S0006297920070111

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