Cargando…

Development of 6′-N-Acylated Isepamicin Analogs with Improved Antibacterial Activity against Isepamicin-Resistant Pathogens

The development of new aminoglycoside (AG) antibiotics has been required to overcome the resistance mechanism of AG-modifying enzymes (AMEs) of AG-resistant pathogens. The AG acetyltransferase, AAC(6′)-APH(2″), one of the most typical AMEs, exhibiting substrate promiscuity towards a variety of AGs a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ban, Yeon Hee, Song, Myoung Chong, Kim, Hee Jin, Lee, Heejeong, Wi, Jae Bok, Park, Je Won, Lee, Dong Gun, Yoon, Yeo Joon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356214/ https://www.ncbi.nlm.nih.gov/pubmed/32545254 http://dx.doi.org/10.3390/biom10060893

Ejemplares similares

In-vitro Activity of Isepamicin against Gram-negative Bacteria in Comparison to Other Aminoglycosides Routinely used at a Teaching Hospital in Northern India
por: Siddiqui, Tasneem, et al.
Publicado: (2023)

Microbial Enzymatic Synthesis of Amikacin Analogs With Antibacterial Activity Against Multidrug-Resistant Pathogens
por: Ban, Yeon Hee, et al.
Publicado: (2021)

Analogs of Periplanetasin-4 Exhibit Deteriorated Membrane-Targeted Action
por: Lee, Heejeong, et al.
Publicado: (2020)

Periplanetasin-2 Enhances the Antibacterial Properties of Vancomycin or Chloramphenicol in Escherichia coli
por: Lee, Heejeong, et al.
Publicado: (2021)

High-yield production of multiple O-methylated phenylpropanoids by the engineered Escherichia coli–Streptomyces cocultivation system
por: Cui, Heqing, et al.
Publicado: (2019)

Complete reconstitution of the diverse pathways of gentamicin B biosynthesis
por: Ban, Yeon Hee, et al.
Publicado: (2019)

Antibacterial activity of ceramide and ceramide analogs against pathogenic Neisseria
por: Becam, Jérôme, et al.
Publicado: (2017)

Whole-genome sequencing and analysis of Streptomyces strains producing multiple antinematode drugs
por: Yi, Jeong Sang, et al.
Publicado: (2022)

Relationship Analogy between Sleep Bruxism and Temporomandibular Disorders in Children: A Narrative Review
por: Lee, Yeon-Hee
Publicado: (2022)

Antibacterial Activity of N,O-Acylated Chitosan Derivative
por: Piegat, Agnieszka, et al.
Publicado: (2020)

Peptaibol Analogs Show Potent Antibacterial Activity against Multidrug Resistant Opportunistic Pathogens
por: Dalla Torre, Chiara, et al.
Publicado: (2023)

Tunable metasurfaces for visible and SWIR applications
por: Lee, Chang-Won, et al.
Publicado: (2020)

Antibacterial and Antibiofilm Activities of Makaluvamine Analogs
por: Nijampatnam, Bhavitavya, et al.
Publicado: (2014)

Suppression of FoxO1 Activity by Long-Chain Fatty Acyl Analogs
por: Zatara, Ghadeer, et al.
Publicado: (2011)

Antibacterial and Antifungal Activities of New Acylated Derivatives of Epigallocatechin Gallate
por: Matsumoto, Yoshimi, et al.
Publicado: (2012)

Acylated flavonol glycosides from Tagetes minuta with antibacterial activity
por: Shahzadi, Irum, et al.
Publicado: (2015)

The Mechanism Underlying the Antibacterial Activity of Shikonin against Methicillin-Resistant Staphylococcus aureus
por: Lee, Young-Seob, et al.
Publicado: (2015)

Identification of genes concordantly expressed with Atoh1 during inner ear development
por: Yoon, Heejei, et al.
Publicado: (2011)

Cytomegalovirus Infections after Hematopoietic Stem Cell Transplantation: Current Status and Future Immunotherapy
por: Cho, Sung-Yeon, et al.
Publicado: (2019)

Design and Synthesis of New Acyl Urea Analogs as Potential σ1R Ligands
por: Thapa, Rajesh, et al.
Publicado: (2023)

Synthesis and Antibacterial Activity of Polyalthic Acid Analogs
por: Argentin, Marcela Nunes, et al.
Publicado: (2023)

Lipase-catalyzed acylation of levoglucosan in continuous flow: antibacterial and biosurfactant studies
por: do Nascimento, Marcelo A., et al.
Publicado: (2022)

A nanohybrid system for taste masking of sildenafil
por: Lee, Ji-Hee, et al.
Publicado: (2012)

Anti-Melanogenic Properties of Velutin and Its Analogs †
por: Jung, Se-Hui, et al.
Publicado: (2021)

Insect immune resolution with EpOME/DiHOME and its dysregulation by their analogs leading to pathogen hypersensitivity
por: Hrithrik, Tafim Hossain, et al.
Publicado: (2023)

Fabrication of Antibacterial Nanofibrous Membrane Infused with Essential Oil Extracted from Tea Tree for Packaging Applications
por: Lee, Ji Yeon, et al.
Publicado: (2020)

Antipathogenic Compounds That Are Effective at Very Low Concentrations and Have Both Antibiofilm and Antivirulence Effects against Pseudomonas aeruginosa
por: Hwang, Hyeon-Ji, et al.
Publicado: (2021)

Design of Protegrin-1 Analogs with Improved Antibacterial Selectivity
por: Bolosov, Ilia A., et al.
Publicado: (2023)

Effect of Abalone Hydrolysates Encapsulated by Double Emulsion on the Physicochemical and Sensorial Properties of Fresh Cheese
por: Choi, HeeJeong, et al.
Publicado: (2017)

Enhanced Ohmyungsamycin A Production via Adenylation Domain Engineering and Optimization of Culture Conditions
por: Kim, Eunji, et al.
Publicado: (2021)

Fatal Breakthrough Mucormycosis in an Acute Myelogenous Leukemia Patient while on Posaconazole Prophylaxis
por: Kang, Seung Hun, et al.
Publicado: (2015)

Clinical significance of germline telomere length and associated genetic factors in patients with neuroblastoma
por: Bae, Joon Seol, et al.
Publicado: (2022)

Biophysical characterization of antibacterial compounds derived from pathogenic fungi Ganoderma boninense
por: Abdullah, Syahriel, et al.
Publicado: (2020)

Gambogic Acid and Its Analogs Inhibit Gap Junctional Intercellular Communication
por: Choi, Eun J., et al.
Publicado: (2018)

Design, Synthesis, and Biological Evaluation of N-Acyl-Homoserine Lactone Analogs of Quorum Sensing in Pseudomonas aeruginosa
por: Wei, Zhenyu, et al.
Publicado: (2022)

Quorum-sensing effector pyocyanin but not farnesol & acyl homoserine lactone exhibit antibacterial activity
por: Kahlon, Nakshdeep Kaur, et al.
Publicado: (2022)

N-Acylated Ciprofloxacin Derivatives: Synthesis and In Vitro Biological Evaluation as Antibacterial and Anticancer Agents
por: Struga, Marta, et al.
Publicado: (2023)

Secondary structure of the Irf7 5’-UTR, analyzed using SHAPE (selective 2’-hydroxyl acylation analyzed by primer extension)
por: Kim, Yun-Mi, et al.
Publicado: (2014)

Development of Clustered Resistance Gene Analogs-Based Markers of Resistance to Phytophthora capsici in Chili Pepper
por: Kim, Nayoung, et al.
Publicado: (2019)

Phage-Derived Antibacterials: Harnessing the Simplicity, Plasticity, and Diversity of Phages
por: Kim, Bi-o, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_aebb338ge1ipp6sbbld34rjatb