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Emerging Roles of RNA 3′-end Cleavage and Polyadenylation in Pathogenesis, Diagnosis and Therapy of Human Disorders

A crucial feature of gene expression involves RNA processing to produce 3′ ends through a process termed 3′ end cleavage and polyadenylation (CPA). This ensures the nascent RNA molecule can exit the nucleus and be translated to ultimately give rise to a protein which can execute a function. Further,...

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Detalles Bibliográficos
Autores principales: Nourse, Jamie, Spada, Stefano, Danckwardt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356254/
https://www.ncbi.nlm.nih.gov/pubmed/32560344
http://dx.doi.org/10.3390/biom10060915