Inducible deletion of skeletal muscle AMPKα reveals that AMPK is required for nucleotide balance but dispensable for muscle glucose uptake and fat oxidation during exercise

OBJECTIVE: Evidence for AMP-activated protein kinase (AMPK)-mediated regulation of skeletal muscle metabolism during exercise is mainly based on transgenic mouse models with chronic (lifelong) disruption of AMPK function. Findings based on such models are potentially biased by secondary effects rela...

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Detalles Bibliográficos
Autores principales: Hingst, Janne R., Kjøbsted, Rasmus, Birk, Jesper B., Jørgensen, Nicolas O., Larsen, Magnus R., Kido, Kohei, Larsen, Jeppe Kjærgaard, Kjeldsen, Sasha A.S., Fentz, Joachim, Frøsig, Christian, Holm, Stephanie, Fritzen, Andreas M., Dohlmann, Tine L., Larsen, Steen, Foretz, Marc, Viollet, Benoit, Schjerling, Peter, Overby, Peter, Halling, Jens F., Pilegaard, Henriette, Hellsten, Ylva, Wojtaszewski, Jørgen F.P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356270/
https://www.ncbi.nlm.nih.gov/pubmed/32504885
http://dx.doi.org/10.1016/j.molmet.2020.101028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356270/
https://www.ncbi.nlm.nih.gov/pubmed/32504885
http://dx.doi.org/10.1016/j.molmet.2020.101028

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