Evaluating the Therapeutic Efficacy of Mono- and Bivalent Affibody-Based Fusion Proteins Targeting HER3 in a Pancreatic Cancer Xenograft Model

Human epidermal growth factor receptor 3 (HER3) has been increasingly scrutinized as a potential drug target since the elucidation of its role in mediating tumor growth and acquired therapy resistance. Affibody molecules are so-called scaffold proteins with favorable biophysical properties, such as...

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Detalles Bibliográficos
Autores principales: Dahlsson Leitao, Charles, S. Rinne, Sara, Altai, Mohamed, Vorontsova, Olga, Dunås, Finn, Jonasson, Per, Tolmachev, Vladimir, Löfblom, John, Ståhl, Stefan, Orlova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356278/
https://www.ncbi.nlm.nih.gov/pubmed/32545760
http://dx.doi.org/10.3390/pharmaceutics12060551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356278/
https://www.ncbi.nlm.nih.gov/pubmed/32545760
http://dx.doi.org/10.3390/pharmaceutics12060551

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