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Uracil-5-yl O-Sulfamate: An Illusive Radiosensitizer. Pitfalls in Modeling the Radiosensitizing Derivatives of Nucleobases

[Image: see text] Efficient radiotherapy requires the concomitant use of ionizing radiation (IR) and a radiosensitizer. In the present work uracil-5-yl O-sulfamate (SU) is tested against its radiosensitizing potential. The compound possesses appropriate dissociative electron attachment (DEA) charact...

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Detalles Bibliográficos
Autores principales: Spisz, Paulina, Zdrowowicz, Magdalena, Kozak, Witold, Chomicz-Mańka, Lidia, Falkiewicz, Karina, Makurat, Samanta, Sikorski, Artur, Wyrzykowski, Dariusz, Rak, Janusz, Arthur-Baidoo, Eugene, Ziegler, Patrick, Rodrigues Costa, Mateus Salomao, Denifl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356320/
https://www.ncbi.nlm.nih.gov/pubmed/32539395
http://dx.doi.org/10.1021/acs.jpcb.0c03844