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Antifungal Agent 4-AN Changes the Genome-Wide Expression Profile, Downregulates Virulence-Associated Genes and Induces Necrosis in Candida albicans Cells

In the light of the increasing occurrence of antifungal resistance, there is an urgent need to search for new therapeutic strategies to overcome this phenomenon. One of the applied approaches is the synthesis of small-molecule compounds showing antifungal properties. Here we present a continuation o...

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Detalles Bibliográficos
Autores principales: Martyna, Aleksandra, Masłyk, Maciej, Janeczko, Monika, Kochanowicz, Elżbieta, Gielniewski, Bartłomiej, Świercz, Aleksandra, Demchuk, Oleg M., Kubiński, Konrad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356344/
https://www.ncbi.nlm.nih.gov/pubmed/32630522
http://dx.doi.org/10.3390/molecules25122928