Bispecific Targeting of EGFR and Urokinase Receptor (uPAR) Using Ligand-Targeted Toxins in Solid Tumors

Ligand-targeted toxins (LTTs) are bioengineered molecules which are composed of a targeting component linked to a toxin that induces cell death once the LTT binds its target. Bispecific targeting allows for the simultaneous targeting of two receptors. In this review, we mostly focus on the epidermal...

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Detalles Bibliográficos
Autores principales: Oh, Felix, Modiano, Jaime F., Bachanova, Veronika, Vallera, Daniel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356355/
https://www.ncbi.nlm.nih.gov/pubmed/32630411
http://dx.doi.org/10.3390/biom10060956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356355/
https://www.ncbi.nlm.nih.gov/pubmed/32630411
http://dx.doi.org/10.3390/biom10060956

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