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Comparative Characterization of Plasmodium falciparum Hsp70-1 Relative to E. coli DnaK Reveals the Functional Specificity of the Parasite Chaperone

Hsp70 is a conserved molecular chaperone. How Hsp70 exhibits specialized functions across species remains to be understood. Plasmodium falciparum Hsp70-1 (PfHsp70-1) and Escherichia coli DnaK are cytosol localized molecular chaperones that are important for the survival of these two organisms. In th...

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Detalles Bibliográficos
Autores principales: Lebepe, Charity Mekgwa, Matambanadzo, Pearl Rutendo, Makhoba, Xolani Henry, Achilonu, Ikechukwu, Zininga, Tawanda, Shonhai, Addmore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356358/
https://www.ncbi.nlm.nih.gov/pubmed/32512819
http://dx.doi.org/10.3390/biom10060856