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Different BCS Class II Drug-Gelucire Solid Dispersions Prepared by Spray Congealing: Evaluation of Solid State Properties and In Vitro Performances

Delivery of poorly water soluble active pharmaceutical ingredients (APIs) by semi-crystalline solid dispersions prepared by spray congealing in form of microparticles (MPs) is an emerging method to increase their oral bioavailability. In this study, solid dispersions based on hydrophilic Gelucires(®...

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Detalles Bibliográficos
Autores principales: Bertoni, Serena, Albertini, Beatrice, Passerini, Nadia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356387/
https://www.ncbi.nlm.nih.gov/pubmed/32545643
http://dx.doi.org/10.3390/pharmaceutics12060548