Synthesis and Spectroscopic Analysis of Piperine- and Piperlongumine-Inspired Natural Product Scaffolds and Their Molecular Docking with IL-1β and NF-κB Proteins

Inspired by the remarkable bioactivities exhibited by the natural products, piperine and piperlongumine, we synthesised eight natural product-inspired analogues to further investigate their structures. For the first time, we confirmed the structure of the key cyclised dihydropyrazolecarbothioamide p...

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Detalles Bibliográficos
Autores principales: Zazeri, Gabriel, Povinelli, Ana Paula R., Le Duff, Cécile S., Tang, Bridget, Cornelio, Marinonio L., Jones, Alan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356504/
https://www.ncbi.nlm.nih.gov/pubmed/32575582
http://dx.doi.org/10.3390/molecules25122841

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356504/
https://www.ncbi.nlm.nih.gov/pubmed/32575582
http://dx.doi.org/10.3390/molecules25122841

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