Methylpiperidinopyrazole Attenuates Estrogen-Induced Mitochondrial Energy Production and Subsequent Osteoblast Maturation via an Estrogen Receptor Alpha-Dependent Mechanism

An estrogen deficiency is the main cause of osteoporosis in postmenopausal women. In bone remodeling, estrogen receptors (ERs) can mediate estrogen-transducing signals. Methylpiperidinopyrazole (MPP) is a highly specific antagonist of ER-alpha (ERα). This study was designed to evaluate the effects o...

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Detalles Bibliográficos
Autores principales: Yeh, Poh-Shiow, Chen, Jui-Tai, Cherng, Yih-Giun, Yang, Shun-Tai, Tai, Yu-Ting, Chen, Ruei-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356510/
https://www.ncbi.nlm.nih.gov/pubmed/32580515
http://dx.doi.org/10.3390/molecules25122876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356510/
https://www.ncbi.nlm.nih.gov/pubmed/32580515
http://dx.doi.org/10.3390/molecules25122876

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