Rapid Clathrin-Mediated Uptake of Recombinant α-Gal-A to Lysosome Activates Autophagy

Enzyme replacement therapy (ERT) with recombinant alpha-galactosidase A (rh-α-Gal A) is the standard treatment for Fabry disease (FD). ERT has shown a significant impact on patients; however, there is still morbidity and mortality in FD, resulting in progressive cardiac, renal, and cerebrovascular p...

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Detalles Bibliográficos
Autores principales: Ivanova, Margarita M., Dao, Julia, Kasaci, Neil, Adewale, Benjamin, Fikry, Jacqueline, Goker-Alpan, Ozlem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356514/
https://www.ncbi.nlm.nih.gov/pubmed/32486191
http://dx.doi.org/10.3390/biom10060837

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356514/
https://www.ncbi.nlm.nih.gov/pubmed/32486191
http://dx.doi.org/10.3390/biom10060837

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